Pigment abnormality is a common problem that patients regularly encounter during my dermatological consultation. One aspect that particularly struck me is the psychological burden associated with visible pigment spots. Having pigment spots can have a major emotional impact. Unfortunately, little data is available on the occurrence of this strain and the factors involved.
Study on pigment spots and anxiety disorder
One study studied 100 patients with various pigment disorders, including both white and dark spots such as vitiligo, melasma, and Acquired Dermal Macular Hyperpigmentation (ADMH).

Using questionnaires, the researchers tried to find out exactly what the influence of their pigment disorders is and how this affects their quality of life, somatoform disorders, general anxiety and depression. A somatoform disorder can be defined as “a mental illness in which a person has physical complaints for which no somatic cause (physical illness) has been found”. The patient therefore experiences real physical complaints, which are not imagined
The results showed that general anxiety disorders occurred in 11.6%, 21% and 18.7% of patients with melasma, vitiligo and ADMH, respectively.
Depression was noted in 12.8%, 27% and 24.1% of patients with melasma, vitiligo and ADMH, respectively.
Somatoform disorders were more common in vitiligo (17.9%) compared to ADMH (14.3%) and melasma (8.1%).
The general trend across all conditions showed a proportional linear relationship between the severity of the skin disease and the intensity of anxiety and depression.
The research shows that pigment disorders in the skin are more than just a cosmetic problem. Anxiety disorders, depression and somatoform disorders are often associated with pigmentary disorders, especially vitiligo and ADMH.
Literature
Research into the impact of melasma: physically and mentally
Three third-year skin therapy students at Utrecht University of Applied Sciences, Loubna, Ouafae and Roos, conducted a study to better understand the influence of melasma on women’s daily lives. To get a good idea of the personal experiences of this target group, they have set up an extensive survey. Their findings show that melasma is not just a skin problem, but can also have a major impact on mental well-being.
Melasma affects more than just the appearance of your skin; it can affect your self-confidence and cause feelings of insecurity, stress and sometimes even depression. Many people experience discomfort in social situations or feel constantly aware of their skin, which complicates their daily lives. It is therefore very important to recognize and address both the physical and emotional sides of melasma.
The good news is that you are not alone. Talking to a dermatologist, skin therapist or people around you can help you better understand and address these feelings. A treatment plan that takes into account both your skin and your mental well-being can provide better results.
Scientific research supports the importance of this integrated approach:
- Chen et al (2024) showed that 43% of people with melasma suffer from feelings of depression. Care providers are advised to pay attention to the mental aspect in addition to the physical treatment.
- Zhu et al. (2022) describes that melasma can lead to avoidance behavior and an obsessive focus on the skin. This can increase feelings of hopelessness and cause people to neglect their skin care, making recovery more difficult.
To support people with melasma, the students have created a closed Facebook group called “Stronger with Melasma”. In this group you can exchange experiences, support each other and receive practical tips. By connecting with others who are going through the same thing, you can build resilience and learn to deal with the challenges that melasma brings.
By paying attention to both the mental and physical aspects of melasma, you can improve not only your skin, but your overall quality of life. Feel free to discuss your feelings and doubts with your healthcare provider and remember: you are not alone.
While you are here
Pigment spots, also known as hyperpigmentation, can appear for a variety of reasons and are often a concern for many. In this article, we take a closer look at the causes of pigment spots and explore effective steps to reduce them and promote an even skin tone. Learn more about the factors that contribute to pigment spots and discover how you can tackle them for a radiant complexion.
Read more here: pigment